Frequently Asked Questions

When can I expect to feel better?

The results should become apparent over 1-3 months but sometimes can take as long as 6-9 months.

How long do Regenexx procedures take?

You can walk right out of the clinic the same day any procedure is completed. The entire process will take anywhere from 2-8 days depending on the doctor’s recommendation.

Do you have any statistics on patient outcomes or success rates?

We do. We have been collecting patient outcome data for quite some time and we regularly and openly publish the results with the public. To view this data, visit our Outcomes Page.

Can you treat more than one area at a time?

This is on a case-by-case basis and although we have before, it would be at the advice of the doctor to treat more than one area. One of the key things that set Regenexx procedures apart is dosage. To ensure the best possible outcome the doctor takes many factors into consideration, including your stem cell count.

Does age make a difference?

Our registry-based research has shown that, for stem cell procedures, older age does not adversely impact outcome.

Are Regenexx procedures covered by insurance?

PRP and stem cell injections are not covered by insurance at this time. However, Regenexx is the only regenerative orthopedic procedure in America that has insurance coverage through some self-funded employers. Please visit regenexxcorporate.com for more information.

Additionally, health insurance plans may cover the initial evaluation. If your plan does, and we are part of your insurance carrier network, we will bill the carrier. If not, there will be a consultation fee for the initial face to face consult.

We recommend that you contact your insurance carrier for more information about your specific coverage details.

Are Regenexx procedures performed in the U.S. approved by the FDA?

Regenexx procedures are exempt from FDA regulation.

Each of the Regenexx procedures available in the United States involves the patient’s own bone marrow or blood, and the Regenexx network of doctors only treat musculoskeletal conditions. Further, none of the Regenexx procedures available in the United States involves the culture expansion of the patient’s cells to create larger number of cells. Thus, the Regenexx procedures available in the United States generally fall into the following regulatory exemptions:

  • For our procedures involving concentrated bone marrow, minimally manipulated bone marrow for homologous use is not subject to FDA regulation as a human cell, tissue, or cellular or tissue-based product (HCT/P); 21 CFR 1271.3(d).
  • For our procedures involving autologous blood (such as PRP), practitioners who are licensed by law to prescribe or administer drugs and who manufacture blood products solely for use in the course of their professional practice are not subject to FDA regulation; 21 CFR 607.65.
  • Procedures involving the removal of an HCT/P from a patient and the implantation of that same HCT/P back into the same patient during the same surgical procedure are not subject to FDA regulation; 21 CFR 1271.15(b).

Regenexx is proud of its history of regulatory compliance and is deeply familiar with the regulatory environment in which it operates. If you have any questions about our regulatory compliance, please feel free to ask and we will be happy to speak with you in further detail.

[Disclaimer: The Regenexx® same-day procedures are performed in the United States. The Regenexx-C cultured stem cell procedure is only offered outside the U.S. through independently owned and operated medical services providers operating exclusively in countries that allow autologous cultured cells to be used through their local regulatory structure. These service providers are not part of nor affiliated with the Centeno-Schultz Clinic nor any U.S. Regenexx Network provider. The Regenexx-C procedure licensed by these entities is not approved by the U.S. FDA for use in the United States.]

Are there known complications?

Using the HHS OHRP guidelines for complications reporting, our complications to date have been in the mild to moderate category and rare. This means that either the complication (like transient swelling) required no medical treatment (Mild), or if it did require medical treatment, the treatment was simple (Moderate-like a patient who failed the procedure who ultimately decided to get the knee replacement that he or she was planning before the procedure).

We have published the world’s largest (to date) safety and complications tracking study of adult stem cell use in patients. This study did not show any serious stem cell-related complications and it did not show that any patient developed a stem cell-related cancer.

In addition, our most recent safety paper was named the best of its type by a meta-analysis that appeared in the prestigious medical journal, Osteoarthritis, and Cartilage.

View the current safety data for our procedures.

How long has Regenexx been doing these procedures?

We originally conducted clinical trials from 2005 – 2007, which were the first orthopedic stem cell procedures performed. Since that time, Regenexx has performed more of these procedures than any other clinic or medical group. The same-day procedure that is currently performed in the United States was developed in 2010 and has been continually improved since that time.

Are Regenexx procedures covered by insurance outside of employer programs?

No, these procedures are too new to be covered yet. Don’t let someone fool you, PRP and stem cell injections have no insurance coverage at this time.

Some health insurance plans may cover the initial evaluation. If your plan does, and we are part of your insurance carrier network, we will bill the carrier. If not, there will be a consultation fee for the initial face to face consult.

We recommend that you contact your insurance carrier for more information about your specific coverage details.

How much do Regenexx procedures cost?

Because the procedure protocol will vary from person to person and because each person will have a unique condition to be treated, the pricing of procedures can vary considerably from patient to patient. An evaluation will give you a better idea of condition, treatment, and costs specific to your condition. The chart below provides a general idea of the procedures and where they fall in terms of cost and severity of conditions treated. Platelet procedures cost considerably less than stem cell procedures.

Are Regenexx procedures painful?

About as painful as a typical shot in a doctor’s office.

How do you know where to place the cells?

We use real-time x-ray known as fluoroscopy or musculoskeletal ultrasound. Your MRI images are used to help plan that injection.

Do I need to have someone drive me?

All of our patients walk out of the clinic. However, having someone drive you for a medical procedure is never a bad idea. On occasion, a local nerve block may be used, which could impair your ability to drive safely, so you should consult with your doctor or clinic about your specific treatment and protocol to ensure that it will be safe for you to drive if you wish to do so.

When can I return to normal activity?

This depends on the type of procedure. However, all of our procedures are designed to promote as much early activity as possible. Here is a general guide:

  • Bone procedure (for fracture non-union or avascular necrosis): You must be off the area on crutches until the pain from the procedure subsides. You can then move toward slowing increasing activities over the next few weeks. Total time off the area for most patients is 1-3 weeks with normal activities at about 6 weeks. The only exception is when there is an existing rod or plate stabilizing the fracture site, in these cases you will be allowed more activity more quickly.
  • Joint procedure: If there is more minimal cartilage loss, low impact activities would be encouraged immediately after the procedure. Full high impact activities would be expected at 4-6 weeks.
  • Partial tendon/ligament/muscle tear: Low impact activities would be encouraged immediately after the procedure. Full high impact activities would be expected at 4-6 weeks.

Is physical therapy needed after a procedure?

In general, we always try to look at more than one injured part. As a result, it’s very likely we will recommend other types of conservative care to restore normal biomechanics. This might include physical therapy, different types of myofascial release, or specific home exercises.

Call 405-697-3436 for more info or to make an appointment

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Surgery-Free Treatment Options

At Orthobiogen, Oklahoma’s only Regenerative Medicine center, we offer advanced surgery-free treatment options for those suffering from spine and joint pain.

We may use your own platelets/PRP and/or bone marrow concentrate (containing your own live stem cells) via regenerative medicine techniques to promote healing and relieve pain. Our goal is to help our patients return to their active lifestyles as quickly and safely as possible.

We offer comprehensive consultations to see if you’re a candidate, so you can get started on your journey to pain-free living today.

Shoulder

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Shoulder Treatments >

Commonly Treated Conditions:

  • Rotator cuff tears
  • Arthritis of the shoulder joint
  • Thoracic outlet syndrome
  • Labral tears or degeneration
  • Rotator cuff tendonitis & tendonosis
  • AC Joint Separation
  • Recurrent shoulder dislocations

Lower Spine

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Spine Treatments >

Commonly Treated Conditions:

  • Lumbar Facet Injury
  • Degenerative Disc Disease
  • Herniated or Bulging Disc
  • Radiculopathy (pinched nerve)
  • SI Joint Syndrome
  • Many More Disc and Low Back Issues

Knee

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Knee Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Meniscus Tears
  • Patellofemoral
  • Syndrome/Chondomalacia
  • ACL Tears + PCL, LCL & MCL Tears & Sprains
  • Patellar Tendonitis
  • Pes anersine bursitis
  • Baker’s cyst
  • Instability
  • Hamstrings Tendinopathy & Biceps Femoris Insertional Tendinopathy

Hip

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Hip Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Osteonecrosis
  • Bursitis
  • Tendinopathy
  • Labral / Labrum Tear

Hand & Wrist

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Hand & Wrist Treatments >

Commonly Treated Conditions:

  • Hand Arthritis
  • Basal Joint Arthritis or CMC / Carpometacarpal
  • Arthritis
  • Instability
  • TFCC Tear
  • Carpal Tunnel SyndromeTrigger Finger

Foot & Ankle

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Foot & Ankle Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Ankle Instability
  • Plantar fasciitis
  • Peroneal tendon tear or split
  • Ligament sprain or tear
  • Sub-talar arthritis or instability
  • Tarsal tunnel syndrome
  • Bunions

Elbow

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Elbow Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Instability
  • Tennis Elbow or Golfer’s Elbow
  • Nerve entrapment (ulnar nerve)

Cervical Spine

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Spine Treatments >

Commonly Treated Conditions:

  • Cervical Instability
  • Cervical Facet Injury
  • Neck, Back or Rib Instability
  • Many More Disc and Cervical Issues Causing Pain